Characterisation of Calcium Phosphate Cement-Derived Hydroxyapatite Scaffolds with a PLGA-Bioactive Glass Composite Coating
نویسندگان
چکیده
منابع مشابه
Incorporation of bioactive glass in calcium phosphate cement: An evaluation.
Bioactive glasses (BGs) are known for their unique ability to bond to living bone. Consequently, the incorporation of BGs into calcium phosphate cement (CPC) was hypothesized to be a feasible approach to improve the biological performance of CPC. Previously, it has been demonstrated that BGs can successfully be introduced into CPC, with or without poly(d,l-lactic-co-glycolic) acid (PLGA) microp...
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BACKGROUND Calcium phosphate cement (CPC) can be molded or injected to form a scaffold in situ, which intimately conforms to complex bone defects. Bioactive glass (BG) is known for its unique ability to bond to living bone and promote bone growth. However, it was not until recently that literature was available regarding CPC-BG applied as an injectable graft. In this paper, we reported a novel ...
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Productions, mechanical and microstructural analyses of bioglass/sheep hydroxyapatite (SHA) composites are introduced. Bioglass were added to calcinated SHA with various concentrations 5 and 10 wt. %. Powder mixture compacted with pressure (350 MPa) in steel moulds to obtain cylinder samples. As the next step, samples sintered in air at various temperatures (1000, 1100, 1200, 1300 C for 4 hrs)....
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Tissue engineering is a multi-disciplinary field, which aims to apply innovative biomaterials to replace or restore ill or damaged tissues of the human body, such as skin and bones. In particular, porous scaffolds are used as temporary 3D templates to support cell attachment and proliferation during the spontaneous regeneration of natural tissues and this approach is particularly promising for ...
متن کاملPolymer-Ceramic Composite Scaffolds: The Effect of Hydroxyapatite and β-tri-Calcium Phosphate
The design of bioactive scaffolds with improved mechanical and biological properties is an important topic of research. This paper investigates the use of polymer-ceramic composite scaffolds for bone tissue engineering. Different ceramic materials (hydroxyapatite (HA) and β-tri-calcium phosphate (TCP)) were mixed with poly-ε-caprolactone (PCL). Scaffolds with different material compositions wer...
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ژورنال
عنوان ژورنال: Journal of Biomimetics, Biomaterials and Tissue Engineering
سال: 2008
ISSN: 1662-100X
DOI: 10.4028/www.scientific.net/jbbte.1.99